ScienceDaily (Sep. 26, 2008) — A link between certain behaviors and the lack of the protein associated with Rett Syndrome – a devastating autism spectrum disorder – demonstrates the importance of MeCP2 (the protein) and reveals never-before recognized functions associated with aggression and obesity, said researchers at Baylor College of Medicine in a report in the current issue of the journal Neuron.
"This protein is critical for the proper function of majority of neurons," said Dr. Huda Y. Zoghbi, a BCM professor of pediatrics, neurology, neuroscience, molecular and human genetics and a Howard Hughes Medical Institute investigator who is senior author on the paper. Zoghbi and her laboratory discovered the Rett gene.
Rett Syndrome affects between 1 in 10,000 females who express a wide variety of symptoms, most of them neurological.
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