Friday, April 24, 2009

Lack Of Key Molecule Leads To Deafness

Inner ears with normal mouse hair cells (left) and without (right). (Credit: Amiel Dror)

ScienceDaily (Apr. 19, 2009) — Despite modern medicine, one in 1,000 American babies are born deaf. The numbers increase markedly with age, with more than 50% of seniors in the United States experiencing some form of hearing loss.

But the era of the hearing aid, and shouting at aging in-laws, may soon be over. A new study by a geneticist and hearing loss expert at Tel Aviv University has uncovered one of the root causes of deafness.

Prof. Karen Avraham of the Department of Human Molecular Genetics, Sackler School of Medicine at Tel Aviv University, has discovered that microRNAs, tiny molecules that regulate cell functions, help us hear. Found in “hair” cells of the ear, this discovery opens an entirely new window for possible treatments, and a cure for all types of deafness, age-related or genetic.

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