Tuesday, May 26, 2009

Down's syndrome reveals one key to fighting cancer

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WASHINGTON (Reuters) – People with Down's syndrome rarely get most kinds of cancer and U.S. researchers have nailed down one reason why -- they have extra copies of a gene that helps keep tumors from feeding themselves.

The findings could lead to new treatments for cancer, the researchers reported in the journal Nature on Wednesday, and further study of Down's patients might reveal more ways to fight tumors.

The researchers at Harvard University and elsewhere made use of a new kind of embryonic-like stem cell called an induced pluripotent stem cell or iPS cell. These cells, made from ordinary skin, can be transformed to act like powerful stem cells, the body's master cells.

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