Obstructive Sleep Apnea Is Prevalent In Adults With Down Syndrome

ScienceDaily (Aug. 17, 2009) — A study in the Aug. 15 issue of the Journal of Clinical Sleep Medicineshows that adults with Down syndrome also frequently suffer from obstructive sleep apnea (OSA). However, complications of untreated OSA such as cardiovascular disease, daytime sleepiness and impaired cognitive functioning overlap with the manifestations of Down syndrome; therefore, OSA may not be detected.

Results indicate that 94 percent of subjects with Down syndrome had OSA; 88 percent had at least moderate OSA with an apnea-hypopnea index (AHI) of more than 15 breathing pauses per hour of sleep; and 69 percent had severe OSA with an AHI of more than 30. Twelve of the 16 subjects with Down syndrome were obese, and there was a significant correlation between body mass index (BMI) and AHI. Total sleep time in subjects with Down syndrome (307 minutes) was more than an hour less than in controls (380 minutes). Despite the severity of OSA in the study group, medical evaluation had been sought in only one case.

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