MONDAY, June 28 (HealthDay News) -- Toddlers who receive the combination MMRV (measles, mumps, rubella and varicella) vaccine are at higher risk of having a febrile seizure a week to 10 days after receiving the shot than children who get the MMR and varicella (chicken pox) vaccines separately at the same visit, a new study confirms.
Although the combination shot doubles the risk of febrile seizure, the odds are still quite small, experts noted.
"What's important for parents to understand is that even though there's a doubling of the risk for the combination vaccine, the overall risk of seizure to any one child with any measles-containing vaccine is still less than one in 1,000 doses," said Dr. Nicola Klein, co-director of the Kaiser Permanente Vaccine Study Center in Oakland, Calif., and lead investigator of the study, published online June 28 and in the July print issue of Pediatrics.
The study, funded by the U.S. Centers for Disease Control and Prevention, involved the health records of more than 459,000 children who received their first dose of measles-containing vaccine between 2000 and 2008. The data came the Vaccine Safety Datalink (VSD), a vaccine safety surveillance system sponsored by the CDC and comprised of health records from eight managed care organizations across the country.
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