Wednesday, March 26, 2008

Non-stimulant curbs ADHD in fragile X syndrome

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NEW YORK (Reuters Health) - L-acetylcarnitine (LAC), a natural substance devoid of side effects, may be considered an alternative to stimulants to control attention deficit hyperactivity disorder (ADHD) in children with the genetic disorder known as fragile X syndrome, researchers conclude based on study they conducted.

Fragile X syndrome is an inherited form of mental retardation. The condition, which may also cause autism and ADHD, results from a genetic defect on the X chromosome.

ADHD is common in young boys with fragile X syndrome and alternatives to methylphenidate and other stimulant medications are needed, note Dr. Giovanni Neri from Universita Cattolica in Rome and colleagues in a Rapid Publication of their study posted online by the American Journal of Medical Genetics.

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