ScienceDaily (Oct. 4, 2009) — Among individuals with mild cognitive impairment, often considered a transitional state between normal cognitive function and Alzheimer's dementia, those who have more difficulties performing routine activities appear more likely to progress quickly to dementia, according to a report in the September issue of Archives of Neurology, one of the JAMA/Archives journals.
Mild cognitive impairment is recognized as a risk factor for dementia and an important public health issue, according to background information in the article. "Annual conversion rates [from mild cognitive impairment to dementia] often range from 10 percent to 15 percent in clinic samples. Conversion rates in community-based studies are often substantially lower (i.e., 3.8 percent to 6.3 percent per year)," the authors write. "Clearly patients with mild cognitive impairment compose a heterogeneous group, of whom not all rapidly convert to dementia. As such, it is important to identify risk factors for progressing rapidly among individuals diagnosed with mild cognitive impairment."
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