UCI neuroscientist Zhiqun Tan lead research that found the retinas of mice may mirror the brain ravaged by Alzheimer's disease. (Credit: Photo by Daniel A. Anderson / University Communications)
ScienceDaily (Oct. 22, 2009) — The eyes may be the windows to the soul, but new research indicates they also may mirror a brain ravaged by Alzheimer's disease.
UC Irvine neuroscientists have found that retinas in mice genetically altered to have Alzheimer's undergo changes similar to those that occur in the brain -- most notably the accumulation of amyloid plaque lesions.
In addition, the scientists discovered that when Alzheimer's therapies are tested in such mice, retinal changes that result might predict how the treatments will work in humans better than changes in mouse brain tissue.
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